I recently went to my doctor because I've been unable to lose weight. I've been on a successful diet, accompanied with a reasonable exercise plan, but I've seen no real results. A series of tests were run — I've got optimum blood pressure, low cholesterol, and I am not diabetic. But, when my cortisol levels were checked — they were very high. The doctor suspected there was a possibility that I might have Cushings' Syndrome — but another test was run and that came up negative.

I was doing research on the internet, and I found that there was a link between excessive cortisol and depression. I was diagnosed with clinical depression when I was 12 (I am now 21). And I am currently untreated. What is the link between cortisol levels and depression? Are excessive cortisol levels a physical manifestation of depression? Or does an excess of cortisol for some other reason cause depression? Does an excessive amount of cortisol cause weight gain, or in my case prohibit weight loss? And if there is a connection — will treatment for my clinical depression (in the form of prescription pills) help me?

I've been unable to find answers anywhere, or at least a good source to tell me to stop worrying — any help would be appreciated.

Thank you for everything, and it is being appreciated by thousands. I have read all your advice to others and have learned a lot. However, I have a problem that I do not know how to handle. It started when I decided to turn myself around from being bisexual to straight (nobody knew what I was, except my best friend, who is also bisexual). I now have a big hole inside me that is being filled by the dark things of life (such as hatred). I had good qualities, such as a great personality, being open-minded, and I would rather go through life without it than turn back to the "bad" habits (please do not get me wrong, I will never judge gays for I have been close to being one). Please help me to fill the hole with life, to get back or improve on my qualities, and to gain the knowledge to approach and attract someone of the opposite sex. And one last thing, do you think it is wise to let my future girlfriend know what I used to be?

I really don't know what to call my situation. Some people say I was molested, others say I was sexually assaulted in the third degree, and others call it sexual misconduct. But when I was thirteen years old, I was touched by a fifteen-year-old boy on the bus for six months. I didn't want this or invite it. I would often fight and say no. He used to fondle my thighs and go into my pants. What is this called? Please e-mail me back.

My best friend has a weight complex. She constantly asks me if I think she's fat and even asks my boyfriend what he thinks of her weight. She isn't overweight and I just wish she would stop worrying about it all the time. Is there anything I can do to convince her she isn't fat?

I compete in an individual sport. The problem is that on the day of a major competition, I have really bad indigestion. Sometimes, I have to run to the bathroom every half hour for a bowel movement! Besides being annoying, disgusting, and a little embarrassing, this interrupts my competition and adds unneeded stress. Why is this happening and what can I do to prevent it?

Recently, I've noticed that my one or two of my friends have taken to cutting themselves. I'm concerned for them... but I've done the same thing in the past and they know it. How do I confront them without sounding like a hypocrite?

1) My boyfriend, who I have been dating for a while now, says that he is fat and I don't think he is. He is built, but he isn't fat. And he talks about it all the time, and I just don't know what to say to him. He said that when he used to talk with his other girlfriend about it, that she would say, "well, go on a diet," and he said that made him feel like he was fat. And I don't want to hurt his feelings, but I know that by losing weight, he would feel better about himself. But I like him for who he is and how he looks. But what should I say to him when he says things like he is fat, do you think I'm fat, etc.?

2) I am a male, 24 years old, height 5'10", and currently I weigh 143 lbs... When I was 17 or so, I weighed a hefty 190 lbs... at that time, that really had a negative effect on my self image, and now at 143, I still don't think I'm thin enough... I have lost all my weight 100 percent through diet and running about 20 miles/week... but I don't eat enough and I always worry before I leave home if I "look ok"? Do I have serious issues?!?

You have an excellent service and give great advice. That is why I feel comfortable asking you this question. About three weeks ago, a group of my friends and I went out to a movie and then a club where we each had some alcohol. After the club, we went back to a friend's room where the group gradually dispersed until there was only myself, two male friends, and one female friend. We began to play sex games. Eventually, we all were naked, on my friend's bed. The female of the group was the center of our activity. She seemed to want it and even encouraged what the three of us started doing to her.

Although we all were tipsy, it was a great sexual experience for all of us, or so I thought. My two male friends have no problem with what happened. The only thing is that my female friend won't speak to us or return any of our calls. I saw her walking down the street the other day and tried to talk to her, but she wouldn't even raise her head to look me in the eye. Do you have any idea what is wrong? Could my friend feel that she was raped? I want to apologize, but I'm not sure what to do.

I find that I get a feeling that I do not know how to explain; it is sort of a sad, discouraged feeling, when I see a black man with a white woman. I am a black female adolescent (20 y/o). I am not a racist. Also, I know of many people both black and white who are not racists but feel the same way. I am not angry at interracial couples when I see them together or anything of that sort. How can I be at ease when I see them, besides that it is not my business? I want to know what possible underlying causes can make people feel this way. How do I unlearn this habit?

I've had sex and I really wish that I'd never done it. I didn't really enjoy it, either. It really hurt and I said I'd never do it again. Will I enjoy it next time?

How is food addiction similar to drug addiction?

I was wondering what the main reason is behind women getting sexually assaulted. Is it because of the way they dress, the way they act, or how easily tricked they are? Do girls say something provocative that entices the male to engage in sexual assault?

I am dating a wonderful, intelligent, and caring man who happens to have cerebral palsy. We are both 20 years old, and this is the first romantic relationship he's been involved in. I am the kind of person who expresses things physically; through hugs, caresses, kisses, etc. Unfortunately, those sort of things make him terribly uncomfortable (psychologically, not physically). He's not used to physical affection and he just doesn't know how to interpret it.

He doesn't see himself as attractive, and it scares him to think that he can be so to anyone, let alone me. Having lived with a disability his entire life, he has pretty much dissociated himself from his body, it having been mainly a source of frustration to him. Is there anything I/he/we can do to help him feel comfortable in and get connected with his body?

I sometimes think about killing people. I don't want to have these thoughts but they go through my mind anyway. I think out ways in my mind to kill them and then kill myself. I would like to know how I can get help without confronting anyone.

Do you believe in going from one relationship that did not work to another, without regrets? How come some people can change their lives without looking back? Is it possible to grow old without regrets?

My father left my mother before I was born. They had a good relationship and were happy, but then my mom became pregnant with me. She had trouble telling my father, who was only eighteen at the time, and said she didn't expect him to play a role in my life. So, he left.

I've never seen him or spoken to him in my life. I have no idea what he looks like or who he is and he seems to have no desire to have anything at all to do with me. In fact, he ditched town the day after he found out. I'm mad... I'm mad at my mother for making it so easy for him to leave and I hate that man for what he did. I'm still young and even I can't imagine deserting a child and leaving them without a parent for their entire life. But then maybe that's because I know how it feels and I would never put anyone through that kind of pain. As a girl, I suppose it's hard to understand. Perhaps you can help me to understand his reasoning?

When I get excited about going to see the boy I love or nervous about hanging out alone with him, I have to poop. Everytime. My stomach gets really upset and it cramps and then I have to poop. In most cases it's diarrhea and I never feel like I'm okay by the time I have to leave. Is there something I can do about it to limit it or just stop it in general? I love knowing that I get to see him but I hate the baggage I get beforehand.

I am a woman who has always been attracted to other women. Until recently, I was attracted to men as well. Now I am almost exclusively attracted to women... which would be fine, except that I think this attraction has a lot to do with painful experiences I’ve had with men. When I was younger, my father was dominant and somewhat abusive, and my first boyfriend was emotionally manipulative and pressured me to have sex with him. After breaking things off with him, I had a very positive sexual relationship with a woman. Am I a lesbian, or am I a bisexual who is just afraid of men? If the latter is true, is there any way to get over this fear?

Whenever I am physically intimate with a girl or even if I suspect eminent intimacy, I begin to tremble uncontrollably. This makes me feel quite awkward and self-conscious. Also this is the only time it happens. Is this a treatable disorder? Is there perhaps some sort of quick fix solution such as getting slightly inebriated before such an encounter?

I am a 22-year-old male who began weight lifting two years ago to get into shape. The problem is I'm still not in shape. I can lift huge amounts of weight, but instead of having a chiseled body, I still look like a fat guy. I mean, I'm big and strong, but I look like I was sculpted from lard (I'm 5'11 and 215 pounds). I do roughly 30 minutes of aerobic activity and about 90 minutes on the weights. Should I change my activity and diet to get leaner?

I'm a 26-year-old male having sex with a 16-year-old girl. Is this against the law?

I'm thinking about seeking therapy for my anxiety and I was wondering if you could talk about the different types of therapists out there. I know the difference between psychologists and psychiatrists is a psychologist didn't go through med-school and so can't prescribe drugs, but what about cognitive-behavior therapists versus... well, whatever else is out there?

Thanks!

1) For the past year now, I have been getting sharp chest pains. Sometimes it feels like I am about to have a heart attack. I find it painful to breathe for the couple of seconds that it happens. The sharp pains occur mostly in the lung/heart area. However, I have also felt them in the lower chest area as well. I don't know what is causing this.

Also, it occurs most frequently during the school year. I should also note that during the school year, I tend to eat greasy fatty foods. However, I had my cholesterol level checked (95) which is low. These pains come any time of day, while I am sleeping, walking, sitting, etc. I am 21-year-old female, if that helps.

By the way, I have a doctor's appointment back home later this month. But I want to have an idea why this happening. Others mentioned to me things about stress, something about a dog's heart, and I was even thinking that it might be cancer.

2) I've recently been experiencing chest pains in the sternum area. Although I don't believe it is related to heart trouble, I think the pain is originating from the bones or muscles attached to the sternum. I have seen doctors but most are clueless as to where the pain may be specifically originating. An interesting side is that during times of stress, the pain is more severe and concentrated at specific points along the sternum. One hypothesis is that the pain may be related to an injured sterno-manubrial joint. If indeed this is the case, what therapy is available to a poor, uninsured student? My mental health is being affected since my once pumped-up, rock hard body is slowly atrophying since I can't lift weights without extreme pain. I'm depressed because the size of my chest is now smaller. What do I do? What's wrong with me?

Sometimes I think what it would be like to be with a man, romantically. I am a single woman, and have never had any relationships. Sometimes, though, when I am imagining what it could be like, it turns violent on me, in my mind, and I always end up being raped. This makes me apprehensive and scared of ever becoming involved with anyone. I am scared that everyone I meet will do this to me. I think that it wouldn't be too bad to be single for the rest of my life, but I want to be loved, to be held. What do you think?